Fibroblast growth factor 8

The Great 2013 Catch-upIn Embryology Gene Control Confounds Evolution (15 April 2013) Jeffrey Tomkins talks at length about a Developmental Cell paper called “An Integrated Holo-Enhancer Unit Defines Tissue and Gene Specificity of the Fgf8 Regulatory Landscape.” No, I don’t know what that means either.

That doesn’t seem to be important, however. Tomkins argument boils down to his classic “complexity = design” line of reasoning that we have seen so many times before. For example:

As noted in a recent press release [link] by the EMBL research institute, “These findings highlight a level of complexity of gene regulation that is often overlooked. Regulatory elements are not engaged in a one-to-one relationship with the specific gene that has the appropriate DNA sequence. The local genomic organization, and 3D folding of DNA, might actually be more important factors that both modulate the action of regulation elements, and put them in contact with their target gene.”

None of this actually means that it could not have evolved, but that doesn’t stop Tomkins from concluding:

Gene networks and the DNA features that control their proper contextual function operate via different genomic regions in a coordinated and complex fashion to provide highly specific three dimensional outcomes. This emerging paradigm is clear evidence of highly elaborate bio-engineering by an omnipotent Creator.

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