Disposable DNA

Skip ahead to the ENCODE stuff if you don’t care for the Tomkins posts.

For his blog post for this week (or last, depending on how you look at it) Jeffrey Tomkins wrote Deleting “Junk DNA” – Does it Matter? I’ll let him explain some of the background:

Does deleting “Junk DNA” in laboratory studies, such as in mice make a difference? Interestingly, a colleague of mine just recently pointed out a paper in which exactly this type of research was undertaken. In fact the study is a few years old, and was done in 2004. However, after a search of the literature, I have not been able to find anything similar.

Because this paper, however, shows up prominently on the web as some sort of proof for “Junk DNA”. I felt that a brief review of the facts that were actually discovered in the research are in order.

I don’t think I’d ever come across the paper – Megabase deletions of gene deserts result in viable mice (pdf) – before, actually. But it does look like it could be useful in future. Let’s see if Tomkins can persuade me against it, shall we? Continue reading