Your Mitochondria May Be Infected

That is to say, according to some studies that a recent paper in Nature cites, an enzyme used in mitochondrial DNA transcription is “distantly related” to that of Bacteriophage T7 (a virus which infects E. coli), a similar enzyme that does the same thing in chloroplasts, and Pol I polymerases generally (whatever they are). This paper itself adds to the table the 3D structure of the human version of the enzyme.

Structure of the human mtRNAP, the enzyme in question. Continue reading